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Sortase A-Cleavable CD1d Identifies Sphingomyelins as Major Class of CD1d-Associated Lipids

CD1d is an atypical MHC class I molecule which binds endogenous and exogenous lipids and can activate natural killer T (NKT) cells through the presentation of lipid antigens. CD1d surveys different cellular compartments including the secretory and the endolysosomal pathway and broadly binds lipids t...

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Detalles Bibliográficos
Autores principales: Rudolph, Maren, Wang, Yuting, Simolka, Theresa, Huc-Claustre, Emilie, Dai, Lingyun, Grotenbreg, Gijsbert, Besra, Gurdyal Singh, Shevchenko, Anna, Shevchenko, Andrej, Zeissig, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9301999/
https://www.ncbi.nlm.nih.gov/pubmed/35874748
http://dx.doi.org/10.3389/fimmu.2022.897873