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Low expression and Hypermethylation of ATP2B1 in Intrahepatic Cholangiocarcinoma Correlated With Cold Tumor Microenvironment

BACKGROUND: The efficacy of current therapeutic schedule is limited owing to fibroproliferative tumor microenvironment (TME) of cholangiocarcinoma, compelling a search for new therapeutic targets. METHODS: Gene expression profiles and methylation profiles were obtained from UCSC Xena. Consensus clus...

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Detalles Bibliográficos
Autores principales: Zhang, Xiehua, He, Yuchao, Ren, Peiqi, Chen, Lu, Han, Zhiqiang, Qi, Lisha, Chen, Liwei, Luo, Yi, Zhang, Ning, Lu, Wei, Guo, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302110/
https://www.ncbi.nlm.nih.gov/pubmed/35875160
http://dx.doi.org/10.3389/fonc.2022.927298