Impact of VKORC1, CYP2C9, CYP1A2, UGT1A1, and GGCX polymorphisms on warfarin maintenance dose: Exploring a new algorithm in South Chinese patients accept mechanical heart valve replacement

Warfarin is the most recommended oral anticoagulant after artificial mechanical valve replacement therapy. However, the narrow therapeutic window and varying safety and efficacy in individuals make dose determination difficult. It may cause adverse events such as hemorrhage or thromboembolism. There...

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Detalles Bibliográficos
Autores principales: Li, Jin, Chen, Tao, Jie, Fangfang, Xiang, Haiyan, Huang, Li, Jiang, Hongfa, Lu, Fei, Zhu, Shuqiang, Wu, Lidong, Tang, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302374/
https://www.ncbi.nlm.nih.gov/pubmed/35866816
http://dx.doi.org/10.1097/MD.0000000000029626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302374/
https://www.ncbi.nlm.nih.gov/pubmed/35866816
http://dx.doi.org/10.1097/MD.0000000000029626

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