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Oncogene Convergence in Extrachromosomal DNA Hubs
Extrachromosomal DNA circles (ecDNA) are a common mechanism for oncogene amplification and are associated with worse clinical outcomes compared with other types of oncogene amplification. Several recent discoveries of ecDNA hubs—local congregations of ecDNAs in the nucleus—highlight unique features...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for Cancer Research
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302380/ https://www.ncbi.nlm.nih.gov/pubmed/35398879 http://dx.doi.org/10.1158/2159-8290.CD-22-0076 |