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Discovery of JND003 as a New Selective Estrogen-Related Receptor α Agonist Alleviating Nonalcoholic Fatty Liver Disease and Insulin Resistance

[Image: see text] Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent forms of chronic liver diseases and is causally linked to hepatic insulin resistance and reduced fatty acid oxidation. Therapeutic treatments targeting both hepatic insulin resistance and lipid oxidative metaboli...

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Detalles Bibliográficos
Autores principales: Mao, Liufeng, Peng, Lijie, Ren, Xiaomei, Chu, Yi, Nie, Tao, Lin, Wanhua, Libby, Andrew, Xu, Yong, Chang, Yu, Lei, Chong, Loomes, Kerry, Wang, Na, Liu, Jinsong, Levi, Moshe, Wu, Donghai, Hui, Xiaoyan, Ding, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302452/
https://www.ncbi.nlm.nih.gov/pubmed/35874496
http://dx.doi.org/10.1021/acsbiomedchemau.1c00050