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Discovery of JND003 as a New Selective Estrogen-Related Receptor α Agonist Alleviating Nonalcoholic Fatty Liver Disease and Insulin Resistance
[Image: see text] Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent forms of chronic liver diseases and is causally linked to hepatic insulin resistance and reduced fatty acid oxidation. Therapeutic treatments targeting both hepatic insulin resistance and lipid oxidative metaboli...
Autores principales: | Mao, Liufeng, Peng, Lijie, Ren, Xiaomei, Chu, Yi, Nie, Tao, Lin, Wanhua, Libby, Andrew, Xu, Yong, Chang, Yu, Lei, Chong, Loomes, Kerry, Wang, Na, Liu, Jinsong, Levi, Moshe, Wu, Donghai, Hui, Xiaoyan, Ding, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302452/ https://www.ncbi.nlm.nih.gov/pubmed/35874496 http://dx.doi.org/10.1021/acsbiomedchemau.1c00050 |
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