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Synthesis of pyrano[3,2-c]quinolones and furo[3,2-c]quinolones via acid-catalyzed tandem reaction of 4-hydroxy-1-methylquinolin-2(1H)-one and propargylic alcohols

Two acid-catalyzed tandem reactions between 4-hydroxy-1-methylquinolin-2(1H)-one and propargylic alcohols are described. Depending mainly on the propargylic alcohol used, these tandem reactions proceed via either a Friedel–Crafts-type allenylation followed by 6-endo-dig cyclization sequence to form...

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Detalles Bibliográficos
Autores principales: Yin, Haiting, Wu, Yunjun, Gu, Xiaoxia, Feng, Zhijun, Wang, Meifang, Feng, Dexiang, Wang, Ming, Cheng, Ziyang, Wang, Shaoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302472/
https://www.ncbi.nlm.nih.gov/pubmed/35919834
http://dx.doi.org/10.1039/d2ra03416f