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Gut Dysbiosis and Intestinal Barrier Dysfunction Promotes IgA Nephropathy by Increasing the Production of Gd-IgA1

BACKGROUND: Immunoglobulin A nephropathy (IgAN) is the most common type of primary glomerular disease in adults worldwide. Several studies have reported that galactose-deficient IgA1 (Gd-IgA1) is involved in the pathogenesis of IgAN. METHODS: Thirty-five patients with IgAN diagnosed with renal biops...

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Detalles Bibliográficos
Autores principales: Tang, Yuyan, Zhu, Yifan, He, Haidong, Peng, Yinshun, Hu, Ping, Wu, Jiajun, Sun, Weiqian, Liu, Ping, Xiao, Yong, Xu, Xudong, Wei, Minggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302483/
https://www.ncbi.nlm.nih.gov/pubmed/35872757
http://dx.doi.org/10.3389/fmed.2022.944027