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The roles of microglia and astrocytes in phagocytosis and myelination: Insights from the cuprizone model of multiple sclerosis

In human demyelinating diseases such as multiple sclerosis (MS), an imbalance between demyelination and remyelination can trigger progressive degenerative processes. The clearance of myelin debris (phagocytosis) from the site of demyelination by microglia is critically important to achieve adequate...

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Detalles Bibliográficos
Autores principales: Sen, Monokesh K., Mahns, David A., Coorssen, Jens R., Shortland, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302634/
https://www.ncbi.nlm.nih.gov/pubmed/35107839
http://dx.doi.org/10.1002/glia.24148