Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model

Amino acids, the building blocks of proteins in the cells and tissues, are of fundamental importance for cell survival, maintenance, and proliferation. The liver plays a critical role in amino acid metabolism and detoxication of byproducts such as ammonia. Urea cycle disorders with hyperammonemia re...

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Detalles Bibliográficos
Autores principales: Mao, Xia, Chen, Helen, Lin, Allen Z., Kim, Sun, Burczynski, Michael E., Na, Erqian, Halasz, Gabor, Sleeman, Mark W., Murphy, Andrew J., Okamoto, Haruka, Cheng, Xiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302672/
https://www.ncbi.nlm.nih.gov/pubmed/34988999
http://dx.doi.org/10.1002/jimd.12474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302672/
https://www.ncbi.nlm.nih.gov/pubmed/34988999
http://dx.doi.org/10.1002/jimd.12474

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