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The accuracy of absolute differential abundance analysis from relative count data
Concerns have been raised about the use of relative abundance data derived from next generation sequencing as a proxy for absolute abundances. For example, in the differential abundance setting, compositional effects in relative abundance data may give rise to spurious differences (false positives)...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302745/ https://www.ncbi.nlm.nih.gov/pubmed/35816553 http://dx.doi.org/10.1371/journal.pcbi.1010284 |