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Potential and action mechanism of favipiravir as an antiviral against Junin virus

Favipiravir is a nucleoside analogue that inhibits the replication and transcription of a broad spectrum of RNA viruses, including pathogenic arenaviruses. In this study, we isolated a favipiravir-resistant mutant of Junin virus (JUNV), which is the causative agent of Argentine hemorrhagic fever, an...

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Detalles Bibliográficos
Autores principales: Zadeh, Vahid Rajabali, Afowowe, Tosin Oladipo, Abe, Haruka, Urata, Shuzo, Yasuda, Jiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302769/
https://www.ncbi.nlm.nih.gov/pubmed/35816544
http://dx.doi.org/10.1371/journal.ppat.1010689