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Orthotopic and Heterotopic Murine Models of Pancreatic Cancer Exhibit Different Immunological Microenvironments and Different Responses to Immunotherapy

For decades, tumor-bearing murine models established using tumor cell lines have been the most commonly used models to study human cancers. Even though there are several studies reported that implant sites caused disparities in tumor behaviors, few of them illuminated the positional effect on immuno...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Liu, Xingchen, Ji, Junsong, Luo, Jianhua, Zhao, Yuanyu, Zhou, Xiaonan, Zheng, Jianming, Guo, Meng, Liu, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302770/
https://www.ncbi.nlm.nih.gov/pubmed/35874730
http://dx.doi.org/10.3389/fimmu.2022.863346