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Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) marks the third novel β-coronavirus to cause significant human mortality in the last two decades. Although vaccines are available, too few have been administered worldwide to keep the virus in check and to prevent mutations leading to immu...

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Detalles Bibliográficos
Autores principales: Piepenbrink, Michael S., Park, Jun-Gyu, Deshpande, Ashlesha, Loos, Andreas, Ye, Chengjin, Basu, Madhubanti, Sarkar, Sanghita, Khalil, Ahmed Magdy, Chauvin, David, Woo, Jennifer, Lovalenti, Philip, Erdmann, Nathaniel B., Goepfert, Paul A., Truong, Vu L., Bowen, Richard A., Walter, Mark R., Martinez-Sobrido, Luis, Kobie, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302814/
https://www.ncbi.nlm.nih.gov/pubmed/35862475
http://dx.doi.org/10.1371/journal.ppat.1010691