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Antimicrobial effects of inhaled sphingosine against Pseudomonas aeruginosa in isolated ventilated and perfused pig lungs

BACKGROUND: Ex-vivo lung perfusion (EVLP) is a save way to verify performance of donor lungs prior to implantation. A major problem of lung transplantation is a donor-to-recipient-transmission of bacterial cultures. Thus, a broadspectrum anti-infective treatment with sphingosine in EVLP might be a n...

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Detalles Bibliográficos
Autores principales: Carstens, Henning, Kalka, Katharina, Verhaegh, Rabea, Schumacher, Fabian, Soddemann, Matthias, Wilker, Barbara, Keitsch, Simone, Sehl, Carolin, Kleuser, Burkhard, Hübler, Michael, Rauen, Ursula, Becker, Anne Katrin, Koch, Achim, Gulbins, Erich, Kamler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302828/
https://www.ncbi.nlm.nih.gov/pubmed/35862397
http://dx.doi.org/10.1371/journal.pone.0271620