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Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light

BACKGROUND AND OBJECTIVES: To evaluate whether plasma biomarkers of amyloid (Aβ42/Aβ40), tau (p-tau181 and p-tau231), and neuroaxonal injury (neurofilament light chain [NfL]) detect brain amyloidosis consistently across racial groups. METHODS: Individuals enrolled in studies of memory and aging who...

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Detalles Bibliográficos
Autores principales: Schindler, Suzanne E., Karikari, Thomas K., Ashton, Nicholas J., Henson, Rachel L., Yarasheski, Kevin E., West, Tim, Meyer, Mathew R., Kirmess, Kristopher M., Li, Yan, Saef, Benjamin, Moulder, Krista L., Bradford, David, Fagan, Anne M., Gordon, Brian A., Benzinger, Tammie L.S., Balls-Berry, Joyce, Bateman, Randall J., Xiong, Chengjie, Zetterberg, Henrik, Blennow, Kaj, Morris, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302933/
https://www.ncbi.nlm.nih.gov/pubmed/35450967
http://dx.doi.org/10.1212/WNL.0000000000200358