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TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts

Sustained exposure of the lung to various environmental or occupational toxins may eventually lead to pulmonary fibrosis, a devastating disease with no cure. Pulmonary fibrosis is characterized by excessive deposition of extracellular matrix (ECM) proteins such as fibronectin and collagens. The pept...

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Detalles Bibliográficos
Autores principales: Zeitlmayr, Sarah, Zierler, Susanna, Staab-Weijnitz, Claudia A., Dietrich, Alexander, Geiger, Fabienne, Horgen, F. David, Gudermann, Thomas, Breit, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302958/
https://www.ncbi.nlm.nih.gov/pubmed/35864199
http://dx.doi.org/10.1007/s00204-022-03342-x