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Non-uniform distribution of dendritic nonlinearities differentially engages thalamostriatal and corticostriatal inputs onto cholinergic interneurons

The tonic activity of striatal cholinergic interneurons (CINs) is modified differentially by their afferent inputs. Although their unitary synaptic currents are identical, in most CINs cortical inputs onto distal dendrites only weakly entrain them, whereas proximal thalamic inputs trigger abrupt pau...

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Detalles Bibliográficos
Autores principales: Oz, Osnat, Matityahu, Lior, Mizrahi-Kliger, Aviv, Kaplan, Alexander, Berkowitz, Noa, Tiroshi, Lior, Bergman, Hagai, Goldberg, Joshua A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302969/
https://www.ncbi.nlm.nih.gov/pubmed/35815934
http://dx.doi.org/10.7554/eLife.76039