Phospholipase activity of acyloxyacyl hydrolase induces IL‐22‐producing CD1a‐autoreactive T cells in individuals with psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by Th17 responses. Recent evidence has identified Langerhans cells to have a key role in disease pathogenesis, with constitutive high expression of CD1a and capacity to present lipid antigens to T cells. Phospholipase A(2) enzymes genera...

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Detalles Bibliográficos
Autores principales: Singh, Randeep, Chen, Yi‐Ling, Ng, Soo Weei, Cain, David, Etherington, Rachel, Hardman, Clare, Ogg, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Immunodeficiencies and autoimmunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302981/
https://www.ncbi.nlm.nih.gov/pubmed/34913478
http://dx.doi.org/10.1002/eji.202149485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302981/
https://www.ncbi.nlm.nih.gov/pubmed/34913478
http://dx.doi.org/10.1002/eji.202149485

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