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Differential sleep/wake response and sex differences following acute suvorexant, MK‐1064 and zolpidem administration in the rTg4510 mouse model of tauopathy

BACKGROUND AND PURPOSE: Transgenic mouse models of tauopathy display prominent sleep/wake disturbances which manifest primarily as a hyperarousal phenotype during the active phase, suggesting that tau pathology contributes to sleep/wake changes. However, no study has yet investigated the effect of s...

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Detalles Bibliográficos
Autores principales: Keenan, Ryan J., Daykin, Heather, Chu, Jiahui, Cornthwaite‐Duncan, Linda, Allocca, Giancarlo, Hoyer, Daniel, Jacobson, Laura H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302982/
https://www.ncbi.nlm.nih.gov/pubmed/35112344
http://dx.doi.org/10.1111/bph.15813