Adult T‐cell leukemia‐lymphoma acquires resistance to DNA demethylating agents through dysregulation of enzymes involved in pyrimidine metabolism

Adult T‐cell leukemia‐lymphoma (ATL) is an aggressive neoplasm derived from T‐cells transformed by human T‐cell lymphotropic virus‐1 (HTLV‐1). Recently, we reported that regional DNA hypermethylation in HTLV‐1‐infected T‐cells reflects the disease status of ATL and the anti‐ATL effects of DNA demeth...

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Detalles Bibliográficos
Autores principales: Yoshida‐Sakai, Nao, Watanabe, Tatsuro, Yamamoto, Yuta, Ureshino, Hiroshi, Kamachi, Kazuharu, Kurahashi, Yuki, Fukuda‐Kurahashi, Yuki, Kimura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Molecular Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303000/
https://www.ncbi.nlm.nih.gov/pubmed/34913485
http://dx.doi.org/10.1002/ijc.33901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303000/
https://www.ncbi.nlm.nih.gov/pubmed/34913485
http://dx.doi.org/10.1002/ijc.33901

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