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Adult T‐cell leukemia‐lymphoma acquires resistance to DNA demethylating agents through dysregulation of enzymes involved in pyrimidine metabolism
Adult T‐cell leukemia‐lymphoma (ATL) is an aggressive neoplasm derived from T‐cells transformed by human T‐cell lymphotropic virus‐1 (HTLV‐1). Recently, we reported that regional DNA hypermethylation in HTLV‐1‐infected T‐cells reflects the disease status of ATL and the anti‐ATL effects of DNA demeth...
Autores principales: | Yoshida‐Sakai, Nao, Watanabe, Tatsuro, Yamamoto, Yuta, Ureshino, Hiroshi, Kamachi, Kazuharu, Kurahashi, Yuki, Fukuda‐Kurahashi, Yuki, Kimura, Shinya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303000/ https://www.ncbi.nlm.nih.gov/pubmed/34913485 http://dx.doi.org/10.1002/ijc.33901 |
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