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Impact of CYBA genotypes on severity and progression of multiple sclerosis

BACKGROUND AND PURPOSE: The NOX2 enzyme of myeloid cells generates reactive oxygen species (ROS) that have been implicated in the pathology of multiple sclerosis (MS). We aimed to determine the impact of genetic variation within CYBA, which encodes the functional CYBA/p22 (phox) subunit of NOX2, on...

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Detalles Bibliográficos
Autores principales: Törnell, Andreas, Kiffin, Roberta, Haghighi, Sara, Mossberg, Natalia, Andersen, Oluf, Hellstrand, Kristoffer, Martner, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303184/
https://www.ncbi.nlm.nih.gov/pubmed/35073438
http://dx.doi.org/10.1111/ene.15259