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Bacterial growth dynamics and pharmacokinetic–pharmacodynamic relationships of rifampicin and bedaquiline in BALB/c mice

BACKGROUND AND PURPOSE: Translational efforts in the evaluation of novel anti‐tubercular drugs demand better integration of pharmacokinetic–pharmacodynamic data arising from preclinical protocols. However, parametric approaches that discriminate drug effect from the underlying bacterial growth dynam...

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Detalles Bibliográficos
Autores principales: Muliaditan, Morris, Della Pasqua, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303191/
https://www.ncbi.nlm.nih.gov/pubmed/34599506
http://dx.doi.org/10.1111/bph.15688