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Sclerostin Protects Against Vascular Calcification Development in Mice

Sclerostin is a negative regulator of the Wnt/β‐catenin signaling and is, therefore, an important inhibitor of bone formation and turnover. Because ectopic vascular calcification develops in a similar way to bone formation, one might reasonably attribute a role to sclerostin in this pathological pro...

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Detalles Bibliográficos
Autores principales: De Maré, Annelies, Opdebeeck, Britt, Neven, Ellen, D’Haese, Patrick C., Verhulst, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303214/
https://www.ncbi.nlm.nih.gov/pubmed/35038187
http://dx.doi.org/10.1002/jbmr.4503