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Selective Disruption of Survivin's Protein‐Protein Interactions: A Supramolecular Approach Based on Guanidiniocarbonylpyrrole

Targeting specific protein binding sites to interfere with protein‐protein interactions (PPIs) is crucial for the rational modulation of biologically relevant processes. Survivin, which is highly overexpressed in most cancer cells and considered to be a key player of carcinogenesis, features two fun...

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Detalles Bibliográficos
Autores principales: Aschmann, Dennis, Vallet, Cecilia, Tripathi, Sunil K., Ruiz‐Blanco, Yasser B., Brabender, Max, Schmuck, Carsten, Sanchez‐Garcia, Elsa, Knauer, Shirley K., Giese, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303230/
https://www.ncbi.nlm.nih.gov/pubmed/35043526
http://dx.doi.org/10.1002/cbic.202100618