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Selective Disruption of Survivin's Protein‐Protein Interactions: A Supramolecular Approach Based on Guanidiniocarbonylpyrrole
Targeting specific protein binding sites to interfere with protein‐protein interactions (PPIs) is crucial for the rational modulation of biologically relevant processes. Survivin, which is highly overexpressed in most cancer cells and considered to be a key player of carcinogenesis, features two fun...
Autores principales: | Aschmann, Dennis, Vallet, Cecilia, Tripathi, Sunil K., Ruiz‐Blanco, Yasser B., Brabender, Max, Schmuck, Carsten, Sanchez‐Garcia, Elsa, Knauer, Shirley K., Giese, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303230/ https://www.ncbi.nlm.nih.gov/pubmed/35043526 http://dx.doi.org/10.1002/cbic.202100618 |
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