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OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency

Histone H3 Lysine 9 (H3K9) methylation, a characteristic mark of heterochromatin, is progressively implemented during development to contribute to cell fate restriction as differentiation proceeds. Accordingly, in undifferentiated and pluripotent mouse Embryonic Stem (ES) cells the global levels of...

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Detalles Bibliográficos
Autores principales: Bernard, Laure D, Dubois, Agnès, Heurtier, Victor, Fischer, Véronique, Gonzalez, Inma, Chervova, Almira, Tachtsidi, Alexandra, Gil, Noa, Owens, Nick, Bates, Lawrence E, Vandormael-Pournin, Sandrine, Silva, José C R, Ulitsky, Igor, Cohen-Tannoudji, Michel, Navarro, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303268/
https://www.ncbi.nlm.nih.gov/pubmed/35762231
http://dx.doi.org/10.1093/nar/gkac550