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DNA barcoded competitive clone-initiating cell analysis reveals novel features of metastatic growth in a cancer xenograft model

A problematic feature of many human cancers is a lack of understanding of mechanisms controlling organ-specific patterns of metastasis, despite recent progress in identifying many mutations and transcriptional programs shown to confer this potential. To address this gap, we developed a methodology t...

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Detalles Bibliográficos
Autores principales: Aalam, Syed Mohammed Musheer, Tang, Xiaojia, Song, Jianning, Ray, Upasana, Russell, Stephen J, Weroha, S John, Bakkum-Gamez, Jamie, Shridhar, Viji, Sherman, Mark E, Eaves, Connie J, Knapp, David J H F, Kalari, Krishna R, Kannan, Nagarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303272/
https://www.ncbi.nlm.nih.gov/pubmed/35875052
http://dx.doi.org/10.1093/narcan/zcac022