Determination of human DNA replication origin position and efficiency reveals principles of initiation zone organisation

Replication of the human genome initiates within broad zones of ∼150 kb. The extent to which firing of individual DNA replication origins within initiation zones is spatially stochastic or localised at defined sites remains a matter of debate. A thorough characterisation of the dynamic activation of...

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Detalles Bibliográficos
Autores principales: Guilbaud, Guillaume, Murat, Pierre, Wilkes, Helen S, Lerner, Leticia Koch, Sale, Julian E, Krude, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303276/
https://www.ncbi.nlm.nih.gov/pubmed/35801867
http://dx.doi.org/10.1093/nar/gkac555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303276/
https://www.ncbi.nlm.nih.gov/pubmed/35801867
http://dx.doi.org/10.1093/nar/gkac555

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