Structural analysis of the basal state of the Artemis:DNA-PKcs complex

Artemis nuclease and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are key components in nonhomologous DNA end joining (NHEJ), the major repair mechanism for double-strand DNA breaks. Artemis activation by DNA-PKcs resolves hairpin DNA ends formed during V(D)J recombination. Artemis defi...

Descripción completa

Detalles Bibliográficos
Autores principales: Watanabe, Go, Lieber, Michael R, Williams, Dewight R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303282/
https://www.ncbi.nlm.nih.gov/pubmed/35801871
http://dx.doi.org/10.1093/nar/gkac564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303282/
https://www.ncbi.nlm.nih.gov/pubmed/35801871
http://dx.doi.org/10.1093/nar/gkac564

Ejemplares similares