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Structural analysis of the basal state of the Artemis:DNA-PKcs complex

Artemis nuclease and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are key components in nonhomologous DNA end joining (NHEJ), the major repair mechanism for double-strand DNA breaks. Artemis activation by DNA-PKcs resolves hairpin DNA ends formed during V(D)J recombination. Artemis defi...

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Detalles Bibliográficos
Autores principales:	Watanabe, Go, Lieber, Michael R, Williams, Dewight R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303282/ https://www.ncbi.nlm.nih.gov/pubmed/35801871 http://dx.doi.org/10.1093/nar/gkac564

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