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Activating natural product synthesis using CRISPR interference and activation systems in Streptomyces

The rise of antibiotic-resistant bacteria represents a major threat to global health, creating an urgent need to discover new antibiotics. Natural products derived from the genus Streptomyces represent a rich and diverse repertoire of chemical molecules from which new antibiotics are likely to be fo...

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Detalles Bibliográficos
Autores principales: Ameruoso, Andrea, Villegas Kcam, Maria Claudia, Cohen, Katherine Piper, Chappell, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303295/
https://www.ncbi.nlm.nih.gov/pubmed/35801861
http://dx.doi.org/10.1093/nar/gkac556