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De novo assembly of human genome at single-cell levels

Genome assembly has been benefited from long-read sequencing technologies with higher accuracy and higher continuity. However, most human genome assembly require large amount of DNAs from homogeneous cell lines without keeping cell heterogeneities, since cell heterogeneity could profoundly affect ha...

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Detalles Bibliográficos
Autores principales: Xie, Haoling, Li, Wen, Hu, Yuqiong, Yang, Cheng, Lu, Jiansen, Guo, Yuqing, Wen, Lu, Tang, Fuchou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303314/
https://www.ncbi.nlm.nih.gov/pubmed/35819189
http://dx.doi.org/10.1093/nar/gkac586