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Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease

BACKGROUND: Parkinson's disease (PD) causes a loss of neuromelanin‐positive, noradrenergic neurons in the locus coeruleus (LC), which has been implicated in nonmotor dysfunction. OBJECTIVES: We used “neuromelanin sensitive” magnetic resonance imaging (MRI) to localize structural disintegration...

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Detalles Bibliográficos
Autores principales: Madelung, Christopher F., Meder, David, Fuglsang, Søren A., Marques, Marta M., Boer, Vincent O., Madsen, Kristoffer H., Petersen, Esben T., Hejl, Anne‐Mette, Løkkegaard, Annemette, Siebner, Hartwig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303353/
https://www.ncbi.nlm.nih.gov/pubmed/35114035
http://dx.doi.org/10.1002/mds.28945