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A molecular beacon assay for monitoring RNA splicing

Small molecule targeting of self-splicing RNAs like group I and II introns has been limited in part by the lack of a universal high-throughput screening platform for studies of splicing inhibition and kinetics. Here, we present the development of a molecular beacon assay for monitoring the accumulat...

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Detalles Bibliográficos
Autores principales: Omran, Qusay Q, Fedorova, Olga, Liu, Tianshuo, Pyle, Anna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303364/
https://www.ncbi.nlm.nih.gov/pubmed/35438748
http://dx.doi.org/10.1093/nar/gkac242