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Measurement of procoagulant platelets provides mechanistic insight and diagnostic potential in heparin‐induced thrombocytopenia

BACKGROUND: Heparin‐induced thrombocytopenia (HIT) is a prothrombotic, immune‐mediated adverse drug reaction associated with high rates of thrombosis‐related morbidity and mortality caused by FcγRIIa‐activating pathogenic antibodies to PF4‐heparin. Procoagulant platelets are a platelet subset that p...

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Detalles Bibliográficos
Autores principales: Lee, Christine S. M., Selvadurai, Maria V., Pasalic, Leonardo, Yeung, James, Konda, Maria, Kershaw, Geoffrey W., Favaloro, Emmanuel J., Chen, Vivien M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303365/
https://www.ncbi.nlm.nih.gov/pubmed/35038779
http://dx.doi.org/10.1111/jth.15650