Cargando…

Regulation of both transcription and RNA turnover contribute to germline specification

The nuanced mechanisms driving primordial germ cells (PGC) specification remain incompletely understood since genome-wide transcriptional regulation in developing PGCs has previously only been defined indirectly. Here, using SLAMseq analysis, we determined genome-wide transcription rates during the...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Kun, Wilkinson, Miles F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303369/
https://www.ncbi.nlm.nih.gov/pubmed/35776114
http://dx.doi.org/10.1093/nar/gkac542