A combinatorial system to examine the enzymatic repair of multiply damaged DNA substrates

DNA damage drives genetic mutations that underlie the development of cancer in humans. Multiple pathways have been described in mammalian cells which can repair this damage. However, most work to date has focused upon single lesions in DNA. We present here a combinatorial system which allows assembl...

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Detalles Bibliográficos
Autores principales: Hsu, Chia Wei, Conrad, James W, Sowers, Mark L, Baljinnyam, Tuvshintugs, Herring, Jason L, Hackfeld, Linda C, Hatch, Sandra S, Sowers, Lawrence C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303388/
https://www.ncbi.nlm.nih.gov/pubmed/35776119
http://dx.doi.org/10.1093/nar/gkac530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303388/
https://www.ncbi.nlm.nih.gov/pubmed/35776119
http://dx.doi.org/10.1093/nar/gkac530

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