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On the stability of stalled RNA polymerase and its removal by RapA

Stalling of the transcription elongation complex formed by DNA, RNA polymerase (RNAP) and RNA presents a serious obstacle to concurrent processes due to the extremely high stability of the DNA-bound polymerase. RapA, known to remove RNAP from DNA in an ATP-dependent fashion, was identified over 50 y...

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Detalles Bibliográficos
Autores principales: Portman, James R, Qayyum, M Zuhaib, Murakami, Katsuhiko S, Strick, Terence R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303389/
https://www.ncbi.nlm.nih.gov/pubmed/35819188
http://dx.doi.org/10.1093/nar/gkac558