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Excess iron promotes emergence of foamy macrophages that overexpress ferritin in the lungs of silicosis patients

BACKGROUND AND OBJECTIVE: Inhalation of high concentrations of respirable crystalline silica (RCS) can lead to silicosis. RCS contains varying levels of iron, which can cause oxidative stress and stimulate ferritin production. This study evaluated iron‐related and inflammatory markers in control and...

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Detalles Bibliográficos
Autores principales: Aloe, Christian Anthony, Leong, Tracy Li‐Tsein, Wimaleswaran, Hari, Papagianis, Paris Clarice, McQualter, Jonathan Luke, McDonald, Christine Faye, Khor, Yet Hong, Hoy, Ryan Francis, Ingle, Aviraj, Bansal, Vipul, Goh, Nicole Soo Leng, Bozinovski, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303595/
https://www.ncbi.nlm.nih.gov/pubmed/35176813
http://dx.doi.org/10.1111/resp.14230