Combining radiation with PI3K isoform-selective inhibitor administration increases radiosensitivity and suppresses tumor growth in non-small cell lung cancer

Non-small cell lung cancer (NSCLC) is a malignant lung tumor with a dismal prognosis. The activation of the phosphoinositide 3-kinase (PI3K)/AKT signaling pathway is common in many tumor types including NSCLC, which results in radioresistance and changes in the tumor microenvironment. Although pan-P...

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Detalles Bibliográficos
Autores principales: Seol, Mi Youn, Choi, Seo Hee, Yoon, Hong In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Fundamental Radiation Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303607/
https://www.ncbi.nlm.nih.gov/pubmed/35536306
http://dx.doi.org/10.1093/jrr/rrac018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303607/
https://www.ncbi.nlm.nih.gov/pubmed/35536306
http://dx.doi.org/10.1093/jrr/rrac018

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