Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation

Design and synthesis of pseudo‐natural products (PNPs) through recombination of natural product (NP) fragments in unprecedented arrangements enables the discovery of novel biologically relevant chemical matter. With a view to wider coverage of NP‐inspired chemical and biological space, we describe t...

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Detalles Bibliográficos
Autores principales: Niggemeyer, Georg, Knyazeva, Anastasia, Gasper, Raphael, Corkery, Dale, Bodenbinder, Pia, Holstein, Julian J., Sievers, Sonja, Wu, Yao‐Wen, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303634/
https://www.ncbi.nlm.nih.gov/pubmed/34978373
http://dx.doi.org/10.1002/anie.202114328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303634/
https://www.ncbi.nlm.nih.gov/pubmed/34978373
http://dx.doi.org/10.1002/anie.202114328

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