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Synthesis of 20‐Membered Macrocyclic Pseudo‐Natural Products Yields Inducers of LC3 Lipidation
Design and synthesis of pseudo‐natural products (PNPs) through recombination of natural product (NP) fragments in unprecedented arrangements enables the discovery of novel biologically relevant chemical matter. With a view to wider coverage of NP‐inspired chemical and biological space, we describe t...
Autores principales: | Niggemeyer, Georg, Knyazeva, Anastasia, Gasper, Raphael, Corkery, Dale, Bodenbinder, Pia, Holstein, Julian J., Sievers, Sonja, Wu, Yao‐Wen, Waldmann, Herbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303634/ https://www.ncbi.nlm.nih.gov/pubmed/34978373 http://dx.doi.org/10.1002/anie.202114328 |
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