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Molecular Determinants of Carbocation Cyclisation in Bacterial Monoterpene Synthases

Monoterpene synthases are often promiscuous enzymes, yielding product mixtures rather than pure compounds due to the nature of the branched reaction mechanism involving reactive carbocations. Two previously identified bacterial monoterpene synthases, a linalool synthase (bLinS) and a cineole synthas...

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Detalles Bibliográficos
Autores principales: Leferink, Nicole G. H., Escorcia, Andrés M., Ouwersloot, Bodi R., Johanissen, Linus O., Hay, Sam, van der Kamp, Marc W., Scrutton, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303655/
https://www.ncbi.nlm.nih.gov/pubmed/35005823
http://dx.doi.org/10.1002/cbic.202100688