Engineered Bacterial Flavin‐Dependent Monooxygenases for the Regiospecific Hydroxylation of Polycyclic Phenols

4‐Hydroxyphenylacetate 3‐hydroxylase (4HPA3H), a flavin‐dependent monooxygenase from E. coli that catalyzes the hydroxylation of monophenols to catechols, was modified by rational redesign to convert also more bulky substrates, especially phenolic natural products like phenylpropanoids, flavones or...

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Detalles Bibliográficos
Autores principales: Herrmann, Susann, Dippe, Martin, Pecher, Pascal, Funke, Evelyn, Pietzsch, Markus, Wessjohann, Ludger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303722/
https://www.ncbi.nlm.nih.gov/pubmed/34979058
http://dx.doi.org/10.1002/cbic.202100480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303722/
https://www.ncbi.nlm.nih.gov/pubmed/34979058
http://dx.doi.org/10.1002/cbic.202100480

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