A Population Pharmacokinetic Model of Vonoprazan: Evaluating the Effects of Race, Disease Status, and Other Covariates on Exposure

Vonoprazan, a potassium‐competitive acid blocker, is under investigation in the United States and Europe for the treatment of erosive esophagitis and Helicobacter pylori infection. Population pharmacokinetic (popPK) analysis allows the identification of factors that could affect drug exposure in pop...

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Detalles Bibliográficos
Autores principales: Scarpignato, Carmelo, Leifke, Eckhard, Smith, Neila, Mulford, Darcy J., Lahu, Gezim, Facius, Axel, Howden, Colin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Pharmacometrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303766/
https://www.ncbi.nlm.nih.gov/pubmed/34935142
http://dx.doi.org/10.1002/jcph.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303766/
https://www.ncbi.nlm.nih.gov/pubmed/34935142
http://dx.doi.org/10.1002/jcph.2019

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