Cargando…

Asymmetrically Substituted m‐Terphenyl Phosphates Inhibit the Transcription Factor STAT5a

We recently presented Stafia‐1 as the first chemical entity that inhibits the transcription factor STAT5a with selectivity over the highly homologous STAT5b. Stafia‐1, which was identified from a series of symmetrically substituted m‐terphenyl phosphates, binds to the interface between the SH2 domai...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller‐Klieser, Daniel, Berg, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303812/
https://www.ncbi.nlm.nih.gov/pubmed/34905258
http://dx.doi.org/10.1002/cbic.202100603