Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision

Retinal photoreceptors have a distinct transcriptomic profile compared to other neuronal subtypes, likely reflecting their unique cellular morphology and function in the detection of light stimuli by way of the ciliary outer segment. We discovered a layer of this molecular specialization by revealin...

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Detalles Bibliográficos
Autores principales: Ciampi, Ludovica, Mantica, Federica, López-Blanch, Laura, Permanyer, Jon, Rodriguez-Marín, Cristina, Zang, Jingjing, Cianferoni, Damiano, Jiménez-Delgado, Senda, Bonnal, Sophie, Miravet-Verde, Samuel, Ruprecht, Verena, Neuhauss, Stephan C. F., Banfi, Sandro, Carrella, Sabrina, Serrano, Luis, Head, Sarah A., Irimia, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303857/
https://www.ncbi.nlm.nih.gov/pubmed/35858306
http://dx.doi.org/10.1073/pnas.2117090119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303857/
https://www.ncbi.nlm.nih.gov/pubmed/35858306
http://dx.doi.org/10.1073/pnas.2117090119

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