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Specialization of the photoreceptor transcriptome by Srrm3-dependent microexons is required for outer segment maintenance and vision
Retinal photoreceptors have a distinct transcriptomic profile compared to other neuronal subtypes, likely reflecting their unique cellular morphology and function in the detection of light stimuli by way of the ciliary outer segment. We discovered a layer of this molecular specialization by revealin...
Autores principales: | Ciampi, Ludovica, Mantica, Federica, López-Blanch, Laura, Permanyer, Jon, Rodriguez-Marín, Cristina, Zang, Jingjing, Cianferoni, Damiano, Jiménez-Delgado, Senda, Bonnal, Sophie, Miravet-Verde, Samuel, Ruprecht, Verena, Neuhauss, Stephan C. F., Banfi, Sandro, Carrella, Sabrina, Serrano, Luis, Head, Sarah A., Irimia, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303857/ https://www.ncbi.nlm.nih.gov/pubmed/35858306 http://dx.doi.org/10.1073/pnas.2117090119 |
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